Test of the isotropy of the speed of light using a continuously rotating optical resonator

We report on a test of Lorentz invariance performed by comparing the resonance frequencies of one stationary optical resonator and one continuously rotating on a precision air bearing turntable. Special attention is paid to the control of rotation induced systematic effects. Within the photon sector of the Standard Model Extension, we obtain improved limits on combinations of 8 parameters at a level of a few parts in $10^{-16}$. For the previously least well known parameter we find $\tilde \kappa_{e-}^{ZZ} =(-1.9 \pm 5.2)\times 10^{-15}$. Within the Robertson-Mansouri-Sexl test theory, our measurement restricts the isotropy violation parameter $\beta -\delta -\frac 12$ to $(-2.1\pm 1.9)\times 10^{-10}$, corresponding to an eightfold improvement with respect to previous non-rotating measurements.Comment: 4 pages, 3 figures, to appear in Phys. Rev. Let

Using machine learning algorithms to determine the post-COVID state of a person by his rhythmogram

In this study we applyed machine-learning algorithms to determine the post-COVID state of a person. During the study, a marker of the post-COVID state of a person was found in the electrocardiogram data. We have shown that this marker in the patient's ECG signal can be used to diagnose a post-COVID state

Blood Biochemistry Analysis to Detect Smoking Status and Quantify Accelerated Aging in Smokers

Abstract There is an association between smoking and cancer, cardiovascular disease and all-cause mortality. However, currently, there are no affordable and informative tests for assessing the effects of smoking on the rate of biological aging. In this study we demonstrate for the first time that smoking status can be predicted using blood biochemistry and cell count results andthe recent advances in artificial intelligence (AI). By employing age-prediction models developed using supervised deep learning techniques, we found that smokers exhibited higher aging rates than nonsmokers, regardless of their cholesterol ratios and fasting glucose levels. We further used those models to quantify the acceleration of biological aging due to tobacco use. Female smokers were predicted to be twice as old as their chronological age compared to nonsmokers, whereas male smokers were predicted to be one and a half times as old as their chronological age compared to nonsmokers. Our findings suggest that deep learning analysis of routine blood tests could complement or even replace the current error-prone method of self-reporting of smoking status and could be expanded to assess the effect of other lifestyle and environmental factors on aging

BOOST -- A Satellite Mission to Test Lorentz Invariance Using High-Performance Optical Frequency References

BOOST (BOOst Symmetry Test) is a proposed satellite mission to search for violations of Lorentz invariance by comparing two optical frequency references. One is based on a long-term stable optical resonator and the other on a hyperfine transition in molecular iodine. This mission will allow to determine several parameters of the standard model extension in the electron sector up to two orders of magnitude better than with the current best experiments. Here, we will give an overview of the mission, the science case and the payload.Comment: 11 pages, 2 figures, accepted for publication in Phys. Rev.

Relativity tests by complementary rotating Michelson-Morley experiments

We report Relativity tests based on data from two simultaneous Michelson-Morley experiments, spanning a period of more than one year. Both were actively rotated on turntables. One (in Berlin, Germany) uses optical Fabry-Perot resonators made of fused silica; the other (in Perth, Australia) uses microwave whispering-gallery sapphire resonators. Within the standard model extension, we obtain simultaneous limits on Lorentz violation for electrons (5 coefficients) and photons (8) at levels down to $10^{-16}$, improved by factors between 3 and 50 compared to previous work.Comment: 5 pages revtex, 2 figure

Vive la radiorésistance!: converging research in radiobiology and biogerontology to enhance human radioresistance for deep space exploration and colonization.

While many efforts have been made to pave the way toward human space colonization, little consideration has been given to the methods of protecting spacefarers against harsh cosmic and local radioactive environments and the high costs associated with protection from the deleterious physiological effects of exposure to high-Linear energy transfer (high-LET) radiation. Herein, we lay the foundations of a roadmap toward enhancing human radioresistance for the purposes of deep space colonization and exploration. We outline future research directions toward the goal of enhancing human radioresistance, including upregulation of endogenous repair and radioprotective mechanisms, possible leeways into gene therapy in order to enhance radioresistance via the translation of exogenous and engineered DNA repair and radioprotective mechanisms, the substitution of organic molecules with fortified isoforms, and methods of slowing metabolic activity while preserving cognitive function. We conclude by presenting the known associations between radioresistance and longevity, and articulating the position that enhancing human radioresistance is likely to extend the healthspan of human spacefarers as well